A potentially novel overlapping gene in the genomes of Israeli acute paralysis virus and its relatives

A potentially novel overlapping gene in the genomes of Israeli acute paralysis virus and its relatives

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asus vivobook r565ea Abstract The Israeli acute paralysis virus (IAPV) is a honeybee-infecting virus that was found to be associated with colony collapse disorder.The IAPV genome contains two genes encoding a structural and a nonstructural polyprotein.We applied a recently developed method for the estimation of selection in overlapping genes to detect purifying selection and, hence, functionality.We provide evolutionary evidence for the existence of a functional overlapping gene, which is translated in the +1 reading frame of the structural polyprotein gene.

Conserved orthologs of this putative gene, which nutella christmas ornament we provisionally call pog (predicted overlapping gene), were also found in the genomes of a monophyletic clade of dicistroviruses that includes IAPV, acute bee paralysis virus, Kashmir bee virus, and Solenopsis invicta (red imported fire ant) virus 1.